By Nancy Lapid
– The next is a abstract of some current research on COVID-19. They embrace analysis that warrants additional research to corroborate the findings and that has but to be licensed by peer overview.
Blood thickness linked with demise danger in extreme COVID-19
Sufferers hospitalized with COVID-19 whose blood flows much less freely than regular are at increased danger of demise from issues, a U.S. research confirmed. The findings point out that measurement of blood viscosity, or blood thickness, must be an everyday a part of these sufferers’ medical work-up, the researchers stated.
Excessive blood viscosity impairs move to small vessels and will increase the danger of blood clots, the researchers famous within the research printed on Monday within the Journal of the American School of Cardiology https://www.sciencedirect.com/science/article/pii/S0735109722051105. Information on 5,621 COVID-19 sufferers handled at six New York Metropolis-area hospitals between February 2020 and November 2021 confirmed that sufferers with excessive viscosity had demise charges 38% to 60% increased than these with low blood viscosity. The irritation related to COVID-19 possible contributes to excessive viscosity, which in flip can result in injury to blood vessel linings and clogging of arteries, in line with the researchers.
“This research demonstrates the significance of checking for blood viscosity in COVID-19 sufferers early in hospital admission, which is well obtained by means of routine lab work,” Dr. Robert Rosenson of the Mount Sinai Well being System stated in an announcement. His crew known as for additional research to see whether or not measures to cut back blood viscosity, akin to remedy with blood thinning medication, can be useful.
Few extra results of COVID-19 booster, flu shot collectively
Individuals who get a flu shot concurrently a COVID-19 mRNA vaccine booster are solely barely extra prone to report negative effects than individuals who get the booster by itself, U.S. researchers discovered. Earlier research discovered that giving flu photographs and COVID-19 vaccines on the identical time didn't make both one much less efficient and could also be extra handy. As reported on Friday within the journal JAMA Community Open https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794318, researchers tracked 981,099 American teenagers and adults who received vaccine boosters with or with out flu photographs in September or October 2021. Within the following week, experiences by research individuals of a “systemic” response akin to fatigue, headache or physique aches have been 8% increased for many who concurrently acquired the flu shot and the Pfizer-BioNTech booster and 11% increased for many who received the flu shot and a Moderna booster, in comparison with the danger in individuals who acquired solely an mRNA vaccine booster. Primarily based on the outcomes, “clinicians can confidently inform sufferers that concurrent administration of the COVID-19 booster and seasonal influenza vaccine is each secure and related to solely a slight improve in opposed occasions in contrast with the COVID-19 booster alone,” a separate crew of researchers wrote in an accompanying editorial https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2794324.
Youngsters with vaccine allergic reactions safely obtain Pfizer photographs
The Pfizer mRNA COVID-19 vaccine might be safely given to youngsters even after a suspected allergic response to the primary dose or a suspected allergy to vaccine components polyethylene glycol (PEG) or polysorbate, in line with immunologists. Different allergists beforehand reported that second doses might be given to adults with suspected reactions to the primary dose. Research outcomes involving a small variety of youngsters have been printed on Wednesday in The Journal of Allergy and Scientific Immunology: In Observe https://www.jaci-inpractice.org/article/S2213-2198(22)00586-4/fulltext. At a specialised vaccine clinic, 9 youngsters have been evaluated after having an allergic response to the primary dose of the vaccine, together with three who skilled probably life-threatening anaphylaxis. All 9 youngsters – together with one who was premedicated – ultimately acquired the second dose “with minimal or no signs,” the researchers stated. One other three youngsters with histories of potential PEG/polysorbate reactions opted to obtain the vaccine on the clinic and tolerated each doses with out allergic signs.
“Any baby who experiences potential anaphylaxis following vaccination ought to completely be evaluated,” research chief Dr. Joel Brooks of Youngsters’s Nationwide Hospital in Washington stated in a information launch. “The advantages and dangers should be weighed fastidiously in terms of a second dose. Nonetheless, now we have demonstrated that for this research, a lot of the preliminary allergic reactions didn't meet the standards of anaphylaxis and our individuals have been in a position to tolerate a second dose of the vaccine.”
Click on for a Reuters International COVID-19 Tracker https://graphics.reuters.com/world-coronavirus-tracker-and-maps/index.html and for a Reuters COVID-19 Vaccination Tracker https://graphics.reuters.com/world-coronavirus-tracker-and-maps/vaccination-rollout-and-access.
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